Lung biopsy without a breathing tube? small study tests a gentler approach
NCT ID NCT05722340
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This pilot study compares two ways to perform a lung biopsy for people with undetermined interstitial lung disease. One method uses a breathing tube and deep anesthesia (standard), while the other uses only mild sedation and numbing medicine. The goal is to see if the gentler method gives biopsy samples that are just as good for making a clear diagnosis. Only 24 adults will take part, and the study focuses on how confident pathologists are in their diagnosis from the tissue samples.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could show that a less invasive anesthesia method (NIVATS) provides equally good biopsy samples for diagnosing lung diseases.
- What could go wrong
- This is a very small pilot study with only 24 participants, so results may not apply widely. The main goal is to compare biopsy quality, not to test a new treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Département d'Anesthésie et Réanimation Cardiothoracique - CHU Arnaud de Villeneuve
Montpellier, France
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