LUNG DISEASES, INTERSTITIAL

This study tests a drug called H01 (hymecromone) in adults with interstitial lung disease, a condition that causes lung scarring and makes breathing hard. The goal is to see if H01 can lower a marker of lung damage and improve lung function. Participants take the drug as a tablet…

This phase 3 trial tests whether belimumab (Benlysta) can stabilize or improve lung function in adults with interstitial lung disease caused by connective tissue diseases like rheumatoid arthritis or lupus. About 440 participants will receive either belimumab injections or a plac…

This early-stage study tests whether inhaling a mist made from donated human amniotic fluid is safe for people with interstitial lung disease (ILD), a condition that scars the lungs and makes breathing hard. About 50 adults aged 40 to 90 with mild to moderate ILD will receive the…

This study looks at how interstitial lung disease (ILD) affects people with rheumatic diseases like rheumatoid arthritis and lupus in Mexico. Researchers will track 312 patients over time to see how the lung disease progresses and what factors might make it worse. The goal is to …

This pilot study compares two ways to perform a lung biopsy for people with undetermined interstitial lung disease. One method uses a breathing tube and deep anesthesia (standard), while the other uses only mild sedation and numbing medicine. The goal is to see if the gentler met…

This study is creating a database to help doctors find early signs of interstitial lung disease (ILD) in people who have other health conditions that put them at risk. About 412 adults with such conditions will be screened and followed over time. The goal is to improve early dete…

This study aims to develop a simple, non-invasive way to detect lung diseases like cancer, asthma, and COPD by analyzing DNA and proteins from cough samples. Researchers will collect cough specimens from 2000 adults, including smokers and non-smokers, and compare them to samples …

This study is creating a registry of medical information from people with interstitial lung disease (ILD). Researchers will collect past, current, and future health records from up to 5,000 adults treated at the UPMC Simmons Center. The goal is to build a database that can be use…