New injection aims to ease lung pressure in scarred lungs

NCT ID NCT07473700

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests an injected drug called TX000045 in 25 people who have high blood pressure in the lungs due to scarring lung disease. The main goal is to see if the drug lowers lung blood pressure and is safe over 16 weeks. Researchers will also check for side effects and changes in heart function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TX000045 (injected drug)

What this could lead to

If it works, this could point toward a new treatment to lower blood pressure in the lungs for people with lung scarring.

What could go wrong

This is a small, early-phase trial with only 25 people, so results may not apply widely. The drug could cause side effects or fail to improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

interstitial lung disease pulmonary hypertension pulmonary hypertension owing to lung disease and/or hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Barcelona

    Barcelona, 08002, Spain

  • Belgrade

    Belgrade, 11000, Serbia

  • Bucharest

    Bucharest, 022328, Romania

  • Krakow

    Krakow, 31-202, Poland

  • Niš

    Niš, 18000, Serbia

  • Scottsdale, Arizona

    Scottsdale, Arizona, 85258, United States