New radioactive drug targets Hard-to-Treat liver cancer

NCT ID NCT06852820

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tests a radioactive drug called 177Lu-PSMA-617 in 10 patients with PSMA-positive liver cancer that has spread. The goal is to see if the drug is safe and can shrink tumors. Patients must have already tried one prior treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
177Lu-PSMA-617 (a radioactive drug)
What this could lead to
If successful, this could point toward a new treatment option for patients with PSMA-positive liver cancer that has spread.
What could go wrong
This is a very small pilot study (10 people) in early Phase 2, so results may not apply broadly. The drug is radioactive and may cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Case Comprehensive Cancer Center, University Hospitals Cleveland Medical Center, Seidman Cancer Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

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