Could a tiny dose of LSD ease PMS? new study investigates
NCT ID NCT07189299
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether very low doses of LSD (10 micrograms) taken daily or every other day during the premenstrual phase can reduce symptoms of severe PMS or PMDD. 150 women will be randomly assigned to LSD or placebo for three menstrual cycles. The goal is to see if LSD can safely ease mood and physical symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LSD (lysergic acid diethylamide)
- What this could lead to
- If it works, this could point toward a new way to manage severe PMS or PMDD symptoms using low-dose LSD during the premenstrual phase.
- What could go wrong
- This is an early-phase study with a small dose and short treatment window. LSD is a controlled substance, and side effects or lack of benefit are possible. Results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Clinical Pharmacology & Toxicology, University Hospital Basel
Basel, Canton of Basel-City, 4056, Switzerland
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Other studies related to the condition(s) this trial covers.