Could a tiny dose of LSD ease PMS? new study investigates

NCT ID NCT07189299

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether very low doses of LSD (10 micrograms) taken daily or every other day during the premenstrual phase can reduce symptoms of severe PMS or PMDD. 150 women will be randomly assigned to LSD or placebo for three menstrual cycles. The goal is to see if LSD can safely ease mood and physical symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LSD (lysergic acid diethylamide)

What this could lead to

If it works, this could point toward a new way to manage severe PMS or PMDD symptoms using low-dose LSD during the premenstrual phase.

What could go wrong

This is an early-phase study with a small dose and short treatment window. LSD is a controlled substance, and side effects or lack of benefit are possible. Results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

polydactyly-myopia syndrome premenstrual dysphoric disorder premenstrual tension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Pharmacology & Toxicology, University Hospital Basel

    Basel, Canton of Basel-City, 4056, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••