Can a lower dose of pregabalin reduce pain and opioid use after surgery?
NCT ID NCT07456761
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether a low dose (82.5 mg) or standard dose (165 mg) of pregabalin retard works better for pain after laparoscopic abdominal surgery. About 80 adults will take one dose before surgery, and researchers will track their pain levels and opioid use for 24 hours. The goal is to find the best dose that controls pain with fewer side effects like dizziness or nausea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pregabalin retard
What this could lead to
If successful, this could show that a lower dose of pregabalin works as well as a higher dose for pain control, with fewer side effects.
What could go wrong
This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The lower dose might not control pain as effectively.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.