Can a lower dose of pregabalin reduce pain and opioid use after surgery?
NCT ID NCT07456761
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether a low dose (82.5 mg) or standard dose (165 mg) of pregabalin retard works better for pain after laparoscopic abdominal surgery. About 80 adults will take one dose before surgery, and researchers will track their pain levels and opioid use for 24 hours. The goal is to find the best dose that controls pain with fewer side effects like dizziness or nausea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pregabalin retard
- What this could lead to
- If successful, this could show that a lower dose of pregabalin works as well as a higher dose for pain control, with fewer side effects.
- What could go wrong
- This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The lower dose might not control pain as effectively.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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