Could a simple infusion after bowel surgery cut opioid use and speed recovery?

NCT ID NCT07434310

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving a drug called dexmedetomidine for 48 hours after laparoscopic bowel surgery helps patients recover better. About 70 adults will receive either the drug or a placebo, and neither they nor their doctors will know which. The main goal is to see if the drug improves overall recovery, reduces pain, and lowers the need for strong opioids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexmedetomidine

What this could lead to

If it works, this could provide a safer, non-opioid way to manage pain after bowel surgery, leading to faster recovery and fewer side effects.

What could go wrong

This is a small, single-center trial. The drug may not improve recovery more than placebo, and it can cause low blood pressure or slow heart rate.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Abdominal Pain inflammatory bowel disease Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact