Could a simple infusion after bowel surgery cut opioid use and speed recovery?

NCT ID NCT07434310

Not yet recruiting Symptom relief Sponsor: Dr. Naveed Siddiqui Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving a drug called dexmedetomidine for 48 hours after laparoscopic bowel surgery helps patients recover better. About 70 adults will receive either the drug or a placebo, and neither they nor their doctors will know which. The main goal is to see if the drug improves overall recovery, reduces pain, and lowers the need for strong opioids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine
What this could lead to: If it works, this could provide a safer, non-opioid way to manage pain after bowel surgery, leading to faster recovery and fewer side effects.
What could go wrong: This is a small, single-center trial. The drug may not improve recovery more than placebo, and it can cause low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Abdominal Pain inflammatory bowel disease Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BOWEL DISEASES, INFLAMMATORY BOWEL SURGERY LAPAROSCOPIC ABDOMINAL SURGERIES

Contacts and locations

Locations

Mount Sinai Hospital

Toronto, Ontario, M5G 1X5, Canada

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