Can Ultra-Low nicotine cigarettes help pregnant smokers cut down?
NCT ID NCT04033237
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving pregnant smokers cigarettes with very low nicotine (0.4 mg per gram of tobacco) helps them smoke less over 12 weeks. Thirty women were randomly assigned to either their usual brand or the low-nicotine cigarettes. The main goal was to see if they smoked fewer cigarettes per day.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
very low nicotine cigarettes (0.4 mg nicotine/g tobacco)
What this could lead to
If successful, this could show that reducing nicotine in cigarettes helps pregnant women smoke less, potentially leading to safer tobacco policies.
What could go wrong
This is a small early-phase study with only 30 participants, so results may not apply to all pregnant smokers. The intervention still involves smoking, which carries health risks.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Kentucky
Lexington, Kentucky, 40536, United States
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University of Vermont
Burlington, Vermont, 05401, United States