Could a lower dose of spinal anesthetic protect elderly patients during surgery?

NCT ID NCT07684989

First seen Jul 06, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This trial compares a low dose versus a standard dose of the spinal anesthetic bupivacaine in adults aged 65 and older undergoing lower leg surgery. The goal is to see if the lower dose reduces dangerous drops in blood pressure and heart rate while still providing effective anesthesia and faster recovery. Participants are randomly assigned to receive either the low or standard dose, and their vital signs and recovery times are closely monitored.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If successful, this could lead to a safer spinal anesthesia method for elderly patients, reducing complications like dangerous drops in blood pressure and speeding up recovery after surgery.
What could go wrong
This is a single-center Phase 4 trial with 180 participants, so results may not apply broadly. The lower dose might not provide enough pain control during surgery.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Hospital, Lahore

    Lahore, Punjab Province, 54950, Pakistan

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