New combo therapy offers hope for tough transplant complication

NCT ID NCT02340676

First seen Oct 31, 2025 · Last updated May 08, 2026 · Updated 25 times

Summary

This study tested whether adding a low dose of Interleukin-2 (IL-2) to a standard therapy called Extra-Corporeal Photopheresis (ECP) could help people with chronic graft-versus-host disease (cGVHD) that did not respond to steroids. cGVHD is a serious condition where donor immune cells attack the recipient's body after a stem cell transplant. The trial enrolled 25 adults and measured how many had a response after 16 weeks of treatment.

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Contacts and locations

Locations

  • Dana-Farber Cancer Insitute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.