Could a tiny dose of buprenorphine spark social drive in schizophrenia?

NCT ID NCT05778591

Recruiting now Symptom relief Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen May 02, 2026 · Last updated May 13, 2026 · Updated 3 times

Summary

This study looks at whether a very low dose of buprenorphine, a drug used for opioid addiction and depression, can boost social motivation in 40 adults with schizophrenia. Many people with this condition struggle with wanting to connect with others or avoiding social situations, and no current medications address this. Participants will take either the drug or a placebo in two lab sessions and complete tasks that measure their social drive. The goal is to see if buprenorphine can help ease this disabling symptom.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SCHIZOPHRENIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UCLA Semel Institute
RECRUITING

Los Angeles, California, 90095, United States

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

SCHIZOPHRENIA