Could a Low-Protein diet boost immunotherapy for melanoma?

NCT ID NCT07586891

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a low branched-chain amino acid (BCAA) diet, when combined with an immunotherapy drug (anti-PD-1), is safe and effective for people with stage III melanoma. About 80 participants will receive either the special diet or a normal diet alongside the immunotherapy. The goal is to see if the diet helps the immune system fight the cancer better, with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low branched-chain amino acid diet and anti-PD-1 monoclonal antibody

What this could lead to

If successful, this combination could improve how well immunotherapy works for stage III melanoma, potentially leading to better tumor shrinkage and longer survival.

What could go wrong

This is a small, early exploratory study with only 80 participants. The diet may not add benefit over standard immunotherapy, and side effects from the combination are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xijing Hospital, Air Force Medical University

    RECRUITING

    Xi'an, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••