Hope for kids with rare bone disorder: new drug shows promise in Long-Term trial

NCT ID NCT07393373

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for children with hypochondroplasia, a condition that causes short stature and bone differences. Researchers are testing a drug called infigratinib to see if it is safe and helps improve growth over the long term. Participants must have already completed a previous study of the same drug. The goal is to understand if the drug can help children grow taller and improve body proportions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bone disorder Dwarfism hereditary disease hypochondroplasia Mucopolysaccharidosis IV musculoskeletal system disorder osteochondrodysplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Astrid Lindgren Children's Hospital

    Solna, 17164, Sweden

  • Centre Hospitalier Universitaire (CHU) de Toulouse - Hôpital des Enfants

    Toulouse, 31059, France

  • Children's Hospital of Eastern Ontario Research Institute

    Ottawa, Ontario, K1H 8L1, Canada

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Childrens Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Glasgow Clinical Research Facility, Queen Elizabeth University Hospital

    Glasgow, Scotland, G51 4TF, United Kingdom

  • Haukeland University Hospital

    Bergen, 5021, Norway

  • Hospital Pediátrico de Coimbra

    Coimbra, 3000-602, Portugal

  • Hôpital Femme Mère Enfant

    Bron, 69677, France

  • Hôpital Universitaire Necker-Enfants Malades

    Paris, 75015, France

  • Johns Hopkins School of Medicine

    Baltimore, Maryland, 21287, United States

  • KK Women's and Children's Hospital

    Singapore, 229899, Singapore

  • London Health Sciences Centre - Children's Hospital of Western Ontario

    London, Ontario, N6C 2R5, Canada

  • Manchester University

    Manchester, England, M13 9WL, United Kingdom

  • Murdoch Children's Research Institute - The Royal Children's Hospital Melbourne

    Parkville, Victoria, 3052, Australia

  • Paediatric Clinical Research Unit at Oslo University Hospital

    Oslo, 0372, Norway

  • Sheffield Children's Hospital

    Sheffield, England, S10 2TH, United Kingdom

  • UCSF Benioff Children's Hospital

    Oakland, California, 94609, United States

  • Unidad de Cirugía Artroscopica, Hopsital MIKS

    Vitoria-Gasteiz, 01010, Spain

  • University of Missouri

    Columbia, Missouri, 65201, United States

  • University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic

    Madison, Wisconsin, 53705, United States

  • Université de Montréal - Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States