New daily pill shows promise for Long-Term psoriatic arthritis control

NCT ID NCT07286058

Recruiting now Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study tests the long-term safety and effectiveness of an oral drug called zasocitinib (TAK-279) in adults with active psoriatic arthritis, a condition causing joint pain and skin patches. About 1,182 participants who completed a one-year parent study will take either a lower or higher dose daily for up to two more years. Researchers will monitor side effects and measure how well the drug controls symptoms over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Zasocitinib (also called TAK-279 or NDI-034858), an oral tablet
What this could lead to: If successful, this could confirm zasocitinib as a safe, long-term daily treatment option to control psoriatic arthritis symptoms and joint damage.
What could go wrong: This is an extension study, so participants already tolerated the drug for a year. However, long-term safety data is still being collected, and rare side effects may emerge over the additional two years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

psoriatic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PSORIATIC ARTHRITIS

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Accurate Clinical Research
RECRUITING

Baytown, Texas, 77521, United States
Advanced Rheumatology of Houston
RECRUITING

The Woodlands, Texas, 77382united, United States
Central South University - Xiangya School of Medicine - Zhuzhou Central Hospital
RECRUITING

Zhuzhou, Hunan, 412007, China
Centro Reumatologico de Caguas
RECRUITING

Caguas, 00725, Puerto Rico
Centrum Medyczne Reuma Park
RECRUITING

Warsaw, 02-665, Poland
Denver Arthritis Clinic - Lowry
RECRUITING

Denver, Colorado, 80230, United States
Direct Helpers Research Center
RECRUITING

Hialeah, Florida, 33012, United States
ETG Warszawa Sp. z o.o.
RECRUITING

Warsaw, 02-677, Poland
First Hospital of Shanxi Medical University
RECRUITING

Taiyuan, Shanxi, 030001, China
First OC Dermatology Research Inc.
RECRUITING

Fountain Valley, California, 92708, United States
GCM Medical Group, PSC
RECRUITING

San Juan, 00917, Puerto Rico
Galilee Medical Center
RECRUITING

Nahariya, 2210001, Israel
Guangzhou First People's Hospital
RECRUITING

Guangzhou, Guangdong, 510180, China
Hamburger Rheuma Forschungszentrum (HRF II) II
RECRUITING

Hamburg, 20095, Germany
INTER CLINIC Piotr Adrian Klimiuk
RECRUITING

Bialystok, 15-077, Poland
IRIS Research and Development
RECRUITING

Plantation, Florida, 33324, United States
Klein and Associates, M.D., P.A.
RECRUITING

Hagerstown, Maryland, 21740-6138, United States
Kyorin University Hospital
RECRUITING

Mitaka-shi, Tokyo-To, 181-8611, Japan
Linyi People's Hospital
RECRUITING

Linyi Shi, Shandong, 276000, China
MEDICAL Plus s.r.o.
RECRUITING

Uherské Hradiště, 68601, Czechia
MICS Centrum Medyczne Torun
RECRUITING

Torun, 87-100, Poland
MTZ Clinical Research Powered by PRATIA - PPDS
RECRUITING

Warsaw, 02-172, Poland
MediTrials OÜ
RECRUITING

Tartu, 50708, Estonia
Mie University Hospital
RECRUITING

Tsu, Mie, Mie-ken, 514-8507, Japan
Nagoya City University Hospital
RECRUITING

Nagoya, Aichi-ken, 467-8602, Japan
National Hospital Organization Tokyo Medical Center
RECRUITING

Meguro-Ku, Tokyo, 152-8902, Japan
Nippon Life Hospital
RECRUITING

Osaka, Osaka, 550-0006, Japan
North Estonia Medical Centre Foundation
RECRUITING

Tallinn, 13419, Estonia
Northwest Houston Arthritis Center
RECRUITING

Houston, Texas, 77090, United States
Novel Research LLC
RECRUITING

Bellaire, Texas, 77401, United States
Novel Research | Abigail Neiman - Houston, TX
RECRUITING

Houston, Texas, 77024, United States
Paramount Medical Research & Consulting, LLC
RECRUITING

Middleburg Heights, Ohio, 44130, United States
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, 100730, China
Peking University Third Hospital
RECRUITING

Beijing, Beijing Municipality, 100191, China
Pratia MCM Krakow
RECRUITING

Krakow, 30-727, Poland
Prywatna Praktyka Lekarska Prof. dr hab. med. Pawel Hrycaj
RECRUITING

Poznan, 61-397, Poland
Purushotham & Akther Kotha MD
RECRUITING

La Mesa, California, 91942, United States
Pv Medical Services
RECRUITING

Zlín, 760 01, Czechia
R.K. Will Pty Ltd
RECRUITING

Victoria Park, Western Australia, 6100, Australia
St. Luke's International Hospital
RECRUITING

Chuo-ku, Tokyo, 104-8560, Japan
Sweet Hope Research Specialty, Inc, d/b/a Neoclinical Research
RECRUITING

Hialeah, Florida, 33016, United States
The Cohen Medical Centers
RECRUITING

Thousand Oaks, California, 91360-3967, United States
Triwest Research Associates LLC
RECRUITING

La Mesa, California, 91942, United States
West Tennessee Research Institute
RECRUITING

Jackson, Tennessee, 38305, United States

Contact Email: •••••@•••••
West Texas Clinical Research
RECRUITING

Lubbock, Texas, 79424, United States

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