Prostate cancer drug safety tracked for years in 700 patients

NCT ID NCT05803941

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 700 adults with prostate cancer who have already received at least one dose of lutetium-177 PSMA-617 in earlier Novartis trials. Researchers will monitor long-term side effects such as dry mouth, eye dryness, bone marrow problems, kidney damage, and new cancers. The goal is to better understand the drug's safety over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lutetium-177 PSMA-617 (a radioactive drug that targets prostate cancer cells)
What this could lead to: If successful, this study will confirm the long-term safety profile of this treatment, helping doctors manage risks like dry mouth, bone marrow suppression, and kidney damage.
What could go wrong: This is an observational follow-up study, not a test of new effectiveness. It only includes people who already tolerated the drug, so results may not apply to all patients. Rare or very late side effects may still be missed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Corewell Health William Beaum Hosp
RECRUITING

Royal Oak, Michigan, 48073-6769, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Hartford Hospital
RECRUITING

Hartford, Connecticut, 06102, United States
Mayo Clinic Arizona
RECRUITING

Scottsdale, Arizona, 85259, United States
Mayo Clinic Jacksonville
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68154, United States
Novartis Investigative Site
RECRUITING

Linz, 4020, Austria
Novartis Investigative Site
RECRUITING

Vienna, 1090, Austria
Novartis Investigative Site
RECRUITING

Ghent, 9000, Belgium
Novartis Investigative Site
RECRUITING

Montreal, Quebec, H2X 1R9, Canada
Novartis Investigative Site
RECRUITING

Olomouc, 779 00, Czechia
Novartis Investigative Site
RECRUITING

Prague, 150 06, Czechia
Novartis Investigative Site
RECRUITING

Lyon, 69373, France
Novartis Investigative Site
RECRUITING

Essen, 45147, Germany
Novartis Investigative Site
RECRUITING

München, 80377, Germany
Novartis Investigative Site
RECRUITING

Rostock, 18057, Germany
Novartis Investigative Site
RECRUITING

Nijmegen, Gelderland, 6500HB, Netherlands
Novartis Investigative Site
RECRUITING

Maastricht, Limburg, 6229 HX, Netherlands
Novartis Investigative Site
RECRUITING

Delft, South Holland, 2625 AD, Netherlands
Novartis Investigative Site
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Novartis Investigative Site
RECRUITING

Sabadell, Barcelona, 08208, Spain
Novartis Investigative Site
RECRUITING

Majadahonda, Madrid, 28222, Spain
Novartis Investigative Site
RECRUITING

Barcelona, 08035, Spain
Novartis Investigative Site
RECRUITING

Barcelona, 08036, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28034, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28040, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28041, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28046, Spain
Novartis Investigative Site
RECRUITING

Valencia, 46026, Spain
Novartis Investigative Site
RECRUITING

Gothenburg, 413 45, Sweden
Novartis Investigative Site
RECRUITING

Stockholm, 17176, Sweden
Novartis Investigative Site
RECRUITING

Sutton, Surrey, SM2 5PT, United Kingdom
Novartis Investigative Site
RECRUITING

Barnet, EN5 3DJ, United Kingdom
Novartis Investigative Site
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Novartis Investigative Site
RECRUITING

Glasgow, G12 0YN, United Kingdom
Novartis Investigative Site
RECRUITING

Middlesbrough, TS4 3BW, United Kingdom
Ochsner Clinic Foundation
RECRUITING

New Orleans, Louisiana, 70121, United States
Onco Hemato Asso of SW Virginia
RECRUITING

Roanoke, Virginia, 24014, United States
Parkview Research Center
RECRUITING

Fort Wayne, Indiana, 46845, United States
Providence Saint Johns Health Ctr
RECRUITING

Santa Monica, California, 90404, United States
St. Joseph Hospital
RECRUITING

Orange, California, 92686, United States
Tulane Cancer Center
RECRUITING

New Orleans, Louisiana, 70112, United States
UT Health Science Center
RECRUITING

Houston, Texas, 77030, United States
Univ of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
Univ of Texas Southwest Med Center
RECRUITING

Dallas, Texas, 75390-9034, United States
University Cancer and Blood Center LLC
RECRUITING

Athens, Georgia, 30607, United States
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of Mississippi Med Ctr
RECRUITING

Jackson, Mississippi, 39216, United States
Urology Cancer Center PC
RECRUITING

Omaha, Nebraska, 68130, United States
VA Medical Center
RECRUITING

Washington D.C., District of Columbia, 20422, United States
Wash U School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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