New drug shows promise for Hard-to-Treat nasal polyps

NCT ID NCT06914908

ENROLLING_BY_INVITATION Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at the long-term safety and effectiveness of lunsekimig, an injectable drug, in adults with chronic sinusitis and nasal polyps that are not well controlled. Participants have already completed a previous lunsekimig study and will continue treatment for up to 52 weeks. The goal is to see if the drug remains safe and helps control symptoms over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lunsekimig (injection) and mometasone furoate nasal spray

What this could lead to

If successful, this could provide a long-term treatment option for people with nasal polyps that are not well controlled by current therapies.

What could go wrong

This is a small, early-phase extension study with no placebo group, so results may not confirm effectiveness. Side effects are still being evaluated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alamo ENT Associates- Site Number : 8400001

    San Antonio, Texas, 78258, United States

  • ENT Associates of Texas - McKinne- Site Number : 8400014

    McKinney, Texas, 75070, United States

  • Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400008

    Norfolk, Virginia, 23510, United States

  • Essential Medical Research- Site Number : 8400020

    Tulsa, Oklahoma, 74137, United States

  • Investigational Site Number : 0320001

    Buenos Aires, 1121, Argentina

  • Investigational Site Number : 0320002

    Rosario, Santa Fe Province, 2000, Argentina

  • Investigational Site Number : 0320003

    Mendoza, 5500, Argentina

  • Investigational Site Number : 0560001

    Leuven, 3000, Belgium

  • Investigational Site Number : 0560002

    Ghent, 9000, Belgium

  • Investigational Site Number : 1000001

    Sofia, 1612, Bulgaria

  • Investigational Site Number : 6160001

    Warsaw, Masovian Voivodeship, 00-909, Poland

  • Investigational Site Number : 6160002

    Krakow, Lesser Poland Voivodeship, 30-033, Poland

  • Investigational Site Number : 6160003

    Katowice, Silesian Voivodeship, 40-611, Poland

  • Investigational Site Number : 6160004

    Poznan, Greater Poland Voivodeship, 60-693, Poland

  • Investigational Site Number : 6160005

    Warsaw, Masovian Voivodeship, 02-507, Poland

  • Investigational Site Number : 6160007

    Wroclaw, Lower Silesian Voivodeship, 50-750, Poland

  • Investigational Site Number : 8260001

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Investigational Site Number : 8260003

    Manchester, M13 9wl, United Kingdom

  • Investigational Site Number : 8260004

    Gloucester, Gloucestershire, GL1 3NN, United Kingdom

  • McGovern Medical School - UT Physicians Dermatology - Bellaire Station- Site Number : 8400017

    Bellaire, Texas, 77401, United States

  • Modena Allergy + Asthma- Site Number : 8400005

    La Jolla, California, 92037, United States

  • Pharmaceutical Research & Consulting- Site Number : 8400004

    Dallas, Texas, 75231, United States

  • Sacramento Ear Nose & Throat - Roseville- Site Number : 8400003

    Roseville, California, 95661, United States

  • Treasure Valley Medical Research- Site Number : 8400002

    Boise, Idaho, 83706, United States