New depression pill shows promise in Long-Term safety check

NCT ID NCT06423781

Completed Disease control Sponsor: Biohaven Therapeutics Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at the long-term safety of a new daily medication called BHV-7000 for people with major depressive disorder. A total of 233 adults who had already completed an earlier study took the pill once a day. Researchers tracked side effects, lab results, and heart changes to see if the drug is safe to take over many months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BHV-7000 (a daily pill)
What this could lead to: If successful, this could point toward a new, long-term treatment option for major depressive disorder.
What could go wrong: This is an early-phase study focused only on safety, not on how well the drug works. The results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Adams Clinical

Watertown, Massachusetts, 02472, United States
Advanced Research Center, Inc.

Anaheim, California, 92805, United States
Aim Trials

Plano, Texas, 75093, United States
Alpine Reseach Organization

Clinton, Utah, 84015, United States
Anderson Clinical Research

Redlands, California, 92374, United States
Arch Clinical Trials

St Louis, Missouri, 63141, United States
Berman Clinical

New York, New York, 10029, United States
Bio Behavioral Health

Toms River, New Jersey, 08755, United States
Bioscience Research LLC

Mount Kisco, New York, 10549, United States
Boston Clinical Trials

Boston, Massachusetts, 02131, United States
CBH Health

Gaithersburg, Maryland, 20877, United States
CIT IE

Riverside, California, 92506, United States
CIT LA

Bellflower, California, 90706, United States
CalNeuro Research Group

Los Angeles, California, 90025, United States
CenExel iResearch, LLC

Decatur, Georgia, 30030, United States
CenExel iResearch, LLC

Savannah, Georgia, 31405, United States
Cenexel CNS

Torrance, California, 90504, United States
Center for Emotional Fitness

Cherry Hill, New Jersey, 08002, United States
Clinical Neuroscience Solutions, Inc

Jacksonville, Florida, 32256, United States
Clinical Neuroscience Solutions, Inc.

Orlando, Florida, 32801, United States
Coastal Carolina Research Center

North Charleston, South Carolina, 29405, United States
Collaborative Neuroscience Research, LLC (CenExel - CNS)

Garden Grove, California, 92845, United States
Collective Medical Research

Overland Park, Kansas, 66210, United States
Copley Clinical

Boston, Massachusetts, 02116, United States
DelRicht Research

New Orleans, Louisiana, 70115, United States
Donald J. Garcia, MD, PA dba Austin Clinical Trial Partners

Austin, Texas, 78737, United States
Excell Research, Inc.

Oceanside, California, 92056, United States
Floridian Neuroscience Institute

Miami Lakes, Florida, 33016, United States
FutureSearch Trials of Dallas

Dallas, Texas, 75234, United States
Grayline Research Center

Wichita Falls, Texas, 76309, United States
Headlands Pharmasite

Baltimore, Maryland, 21208, United States
IMA Clinical Research

Phoenix, Arizona, 85012, United States
IMA Clinical Research

Las Vegas, Nevada, 89102, United States
IPMG

Chino, California, 91710, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
InSite Clinical Research, LLC

DeSoto, Texas, 75115, United States
K2 Medical Research

Tampa, Florida, 33607, United States
Lehigh Center for Clinical Research

Allentown, Pennsylvania, 18104, United States
Lumos Clinical Research Center, LLC

San Jose, California, 95124, United States
MCB Clinical Research Centers

Colorado Springs, Colorado, 80910, United States
Midwest Clinical Research Center

Dayton, Ohio, 45417, United States
NRC Research Institute

Orange, California, 92868, United States
Neurobehavioral Research, Inc

Cedarhurst, New York, 11516, United States
Neuroscience Research Institute

West Palm Beach, Florida, 33407, United States
Northwest Clinical Research Center

Bellevue, Washington, 98007, United States
Optum Behavioral Care of Connecticut, PC dba Comprehensive Psychiatric Care of Connecticut

Norwich, Connecticut, 06360, United States
Pacific Clinical Research Management Group

Upland, California, 91786, United States
Pillar Clinical Research, LLC

Little Rock, Arkansas, 72204, United States
Precise Clinical Research

Flowood, Mississippi, 39232, United States
RBA

Staten Island, New York, 10329, United States
Red Oak Psychiatry Associates, PA

Houston, Texas, 77373, United States
Relaro Medical Trials, LLC

Dallas, Texas, 75243, United States
Reverie Mind, LLC

Chandler, Arizona, 85226, United States
Revive Research Institute, Inc.

Elgin, Illinois, 60123, United States
SPRI Clinical Trials, LLC

Brooklyn, New York, 11235, United States
Scranton Medical Institute

Moosic, Pennsylvania, 18509, United States
Stanford

Stanford, California, 94305, United States
Suburban Research Associates

Media, Pennsylvania, 19063, United States
Summit Headlands LLC

Portland, Oregon, 97210, United States
Sunwise Clinical Research

Walnut Creek, California, 94596, United States
The Medical Research Network, LLC

New York, New York, 10128, United States
UConn Health

Farmington, Connecticut, 06030, United States
Uptown Research Institute

Chicago, Illinois, 60640, United States
WIRG

Little Rock, Arkansas, 72211, United States
WR-PRI Encino

Encino, California, 91316, United States
WRN

Rogers, Arkansas, 72758, United States

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