Could a simple arm cuff boost heart health after bypass?

NCT ID NCT04779008

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing whether doing repeated cycles of arm blood pressure cuff inflation (called remote ischemic preconditioning) over several months can improve blood flow to the heart muscle in people who have had coronary artery bypass surgery. The researchers will measure heart blood flow using imaging scans and track heart-related events for one year. 210 participants who need bypass surgery for three blocked arteries are being recruited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remote ischemic preconditioning (RIPC) - brief cycles of arm blood pressure cuff inflation and deflation

What this could lead to

If it works, this could provide a simple, drug-free way to improve heart blood flow and reduce complications after bypass surgery.

What could go wrong

This is a relatively small, early-stage study. Previous single-dose RIPC did not improve long-term outcomes, and the long-term version may also fail to show benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fuwai central China cardiovascular Hospital

    RECRUITING

    Zhengzhou, Henan, China

    Contact

    Contact Email: •••••@•••••