Could a simple arm cuff boost heart health after bypass?

NCT ID NCT04779008

Recruiting now Disease control Sponsor: Henan Institute of Cardiovascular Epidemiology Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing whether doing repeated cycles of arm blood pressure cuff inflation (called remote ischemic preconditioning) over several months can improve blood flow to the heart muscle in people who have had coronary artery bypass surgery. The researchers will measure heart blood flow using imaging scans and track heart-related events for one year. 210 participants who need bypass surgery for three blocked arteries are being recruited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remote ischemic preconditioning (RIPC) - brief cycles of arm blood pressure cuff inflation and deflation
What this could lead to: If it works, this could provide a simple, drug-free way to improve heart blood flow and reduce complications after bypass surgery.
What could go wrong: This is a relatively small, early-stage study. Previous single-dose RIPC did not improve long-term outcomes, and the long-term version may also fail to show benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY DISEASE

Contacts and locations

Locations

Fuwai central China cardiovascular Hospital
RECRUITING

Zhengzhou, Henan, China

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