Can a daily spleen zap ease long COVID fatigue?
NCT ID NCT06189066
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed pilot study tested a daily ultrasound device applied to the spleen for 8 weeks in 15 adults with Long COVID. The goal was to see if it safely improves symptoms like fatigue, pain, and brain fog. Researchers measured walking endurance and fatigue levels before and after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ultrasound device applied to the spleen
- What this could lead to
- If it works, this could point toward a non-drug way to ease Long COVID symptoms like fatigue and brain fog.
- What could go wrong
- This was a very small pilot study with only 15 people and no comparison group, so results may not be reliable or apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LONG COVID are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Minnesota - Phillips-Wangensteen Building
Minneapolis, Minnesota, 55455, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Five years on: how does long COVID evolve?
- Could exercise retrain the heart in long COVID?
- Can brain games and gentle currents lift long COVID brain fog?
- Can brain training zap long COVID brain fog?
- Ear device zaps vagus nerve in bid to quiet long COVID fatigue and brain fog
- Smartphone therapy could ease long COVID's mental toll