Could a diabetes drug ease long COVID fatigue?
NCT ID NCT07128082
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether tirzepatide (Zepbound), a drug used for diabetes and weight loss, can reduce Long COVID symptoms like fatigue. About 1000 adults with Long COVID will take either the drug or a placebo for 12 months, and all tasks are done remotely. The main goal is to see if fatigue scores improve compared to placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tirzepatide (Zepbound)
What this could lead to
If it works, this could point toward a treatment that reduces fatigue and improves quality of life for people with Long COVID.
What could go wrong
This is a Phase 2 trial, so it is still early. The medication may not work better than a placebo, and side effects from tirzepatide (like nausea or digestive issues) are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Scripps Research
La Jolla, California, 92037, United States