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Machine perfusion could double usable donor livers and cut wait times

NCT ID NCT06874296

Recruiting now Disease control Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a machine that keeps donated livers working outside the body can help doctors safely use livers that were previously considered too risky for transplant. About 186 adults on the liver transplant waiting list will be randomly assigned to either receive a standard transplant or be offered a liver that passed a quality check after at least four hours on the machine. The main goal is to see if this approach shortens the time to transplant and increases the number of usable livers.

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Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER DISEASES LIVER TRANSPLANTATION SURGERY

Contacts and locations

Locations

  • Department of General, Visceral and Transplant Surgery, Hannover Medical School

    RECRUITING

    Hanover, Germany

  • Department of General, Visceral and Transplantation Surgery, LMU University Hospital, LMU Munich

    RECRUITING

    München, Germany

  • Department of General, Visceral, Transplantation, Vascular, and Pediatric Surgery, University Hospital Wurzburg

    RECRUITING

    Würzburg, Germany

  • Department of Surgery Campus Charité Mitte | Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin

    RECRUITING

    Berlin, State of Berlin, 13353, Germany

  • Department of Surgery, University Hospital Regensburg

    RECRUITING

    Regensburg, Germany

  • Eberhard Karls University of Tübingen, Department of General Visceral and Transplant Surgery

    RECRUITING

    Tübingen, Germany

  • University Hospital Bonn

    RECRUITING

    Bonn, North Rhine-Westphalia, 53127, Germany

  • University Hospital Muenster

    RECRUITING

    Münster, North Rhine-Westphalia, 49149, Germany

  • University Hospital RWTH Aachen

    RECRUITING

    Aachen, North Rhine-Westphalia, 52074, Germany

  • University Medical Center Hamburg-Eppendorf

    RECRUITING

    Hamburg, Free and Hanseatic City of Hamburg, 20251, Germany

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