Machine perfusion could double usable donor livers and slash transplant wait times

NCT ID NCT06874296

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This study tests a method called normothermic machine perfusion, which keeps donated livers working outside the body so doctors can check their quality. The goal is to safely use livers that were previously considered unsuitable, helping 186 people on the transplant waiting list get a transplant sooner. Participants are randomly assigned to either receive a machine-checked liver or follow the usual transplant process, and researchers will measure how quickly they get a transplant and how well they do afterward.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of General, Visceral and Transplant Surgery, Hannover Medical School

    RECRUITING

    Hanover, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of General, Visceral and Transplantation Surgery, LMU University Hospital, LMU Munich

    RECRUITING

    München, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of General, Visceral, Transplantation, Vascular, and Pediatric Surgery, University Hospital Wurzburg

    RECRUITING

    Würzburg, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Surgery Campus Charité Mitte | Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin

    RECRUITING

    Berlin, State of Berlin, 13353, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Surgery, University Hospital Regensburg

    RECRUITING

    Regensburg, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Eberhard Karls University of Tübingen, Department of General Visceral and Transplant Surgery

    RECRUITING

    Tübingen, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Bonn

    RECRUITING

    Bonn, North Rhine-Westphalia, 53127, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Muenster

    RECRUITING

    Münster, North Rhine-Westphalia, 49149, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital RWTH Aachen

    RECRUITING

    Aachen, North Rhine-Westphalia, 52074, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Medical Center Hamburg-Eppendorf

    RECRUITING

    Hamburg, Free and Hanseatic City of Hamburg, 20251, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.