Heart drug may ease liver strain in kids with rare condition
NCT ID NCT03430583
First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 23 times
Summary
This study looked at whether a heart medication called udenafil could reduce liver stiffness in 88 children with single ventricle heart disease. Liver stiffness is a sign of liver damage that can happen in these children. The study measured liver stiffness using ultrasound and MRI scans over 52 weeks. Results showed changes in liver stiffness, but this is a disease control study, not a cure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Children's Mercy Hospital
Kansas City, Kansas, 64108, United States
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Children's Mercy Hospital Kansas City
Kansas City, Missouri, 64108, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20008, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Nemours Cardiac Center/Alfred I. duPont Hospital for Children
Wilmington, Delaware, 19803, United States
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Primary Children's Medical Hospital/Dept. of Pediatric Cardiology
Salt Lake City, Utah, 84113, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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The Hospital for Sick Children
Toronto, Ontario, ON M5G 1X8, Canada
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University of Michigan Congenital Heart Center
Ann Arbor, Michigan, 48109-4204, United States
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University of Nebraska Children's Hospital and Medical Center
Omaha, Nebraska, 68114, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.