New triple therapy targets hard-to-treat liver metastases in colorectal cancer

NCT ID NCT07353268

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new combination of an antibody drug (QL1706), a targeted therapy (fruquintinib), and short-course radiotherapy against standard third-line therapy in 76 adults with colorectal cancer that has spread to the liver and cannot be removed by surgery. The goal is to see if the new combo is safer and more effective at delaying cancer growth. Participants must have a specific tumor type (pMMR/MSS) and liver metastases at least 5 cm in size.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••