Liver study reveals how cirrhosis alters medicine breakdown

NCT ID NCT05741385

First seen Sep 30, 2025 · Last updated Apr 29, 2026 · Updated 25 times

Summary

This study looked at how the body handles five common drugs (caffeine, warfarin, omeprazole, metoprolol, and midazolam) in healthy adults and in people with mild or moderate liver cirrhosis. Researchers measured drug levels in the blood to see if liver scarring changes how these medicines are processed. The goal is to help doctors dose future medications safely for patients with liver disease.

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Contacts and locations

Locations

  • CRS Clinical Research Services Mannheim GmbH

    Mannheim, 68167, Germany

Conditions

Explore the condition pages connected to this study.