Freezing tumors before chemo: new hope for esophageal cancer?

NCT ID NCT07222657

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study tests whether freezing cancer cells with liquid nitrogen before chemotherapy can improve outcomes for people with advanced esophageal cancer. About 40 adults will be randomly assigned to receive either the freezing treatment plus chemotherapy or chemotherapy alone. The freezing is done during an endoscopy and aims to destroy tumor tissue, potentially leading to better response rates.

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus esophageal adenocarcinoma esophageal cancer Esophageal Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic Florida

    RECRUITING

    Weston, Florida, 33331, United States

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