Blood test may boost colorectal cancer screening in underserved communities

NCT ID NCT06929481

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether offering a blood test (cell free DNA) alongside standard stool tests and colonoscopy increases colorectal cancer screening rates among people who are not up-to-date with screening. The trial enrolls 340 adults aged 45-75 at a health center serving low-income and minority groups. Participants are randomly assigned to receive either standard screening options or expanded options that include the blood test, and researchers will compare how many complete screening within 60 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cell free DNA (cfDNA) blood test

What this could lead to

If successful, this could show that offering a simple blood test increases colorectal cancer screening rates among groups who currently face barriers, helping reduce health disparities.

What could go wrong

This is a small, early-stage pragmatic trial focused on screening completion, not cancer detection or survival. The blood test is less sensitive for advanced polyps than colonoscopy, so it may miss some precancerous growths.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal neoplasm colorectal cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Family Health Centers of San Diego, Logan Heights site

    San Diego, California, 92113, United States