Blood test could help spot brain tumor growth vs. treatment side effects

NCT ID NCT07417774

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: NuvOx LLC Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is part of a larger trial testing an oxygen-boosting drug called NanO2 in people with glioblastoma, a serious brain cancer. Researchers will analyze blood samples from 40 patients to find markers that show how low oxygen levels in the tumor affect the disease. They also hope to find a way to tell the difference between true tumor growth and pseudoprogression, which looks like growth on scans but is actually a treatment reaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NanO2 (oxygen therapeutic)
What this could lead to: If successful, this could help doctors tell the difference between actual tumor growth and treatment-related changes in glioblastoma patients, leading to more accurate monitoring.
What could go wrong: This is a small, early-stage biomarker study, not a treatment trial. The findings may not lead to immediate clinical changes or benefit participants directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA (GBM)

Contacts and locations

Locations

Center for Neurosciences

Tucson, Arizona, 85718, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Saint Luke's Cancer Institute

Kansas City, Missouri, 64111, United States
Yale Cancer Center

New Haven, Connecticut, 06520, United States

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