Blood test could replace brain surgery for tumor tracking
NCT ID NCT05925218
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to develop a liquid biopsy—a blood test—to detect tumor DNA in patients with high-grade gliomas, an aggressive type of brain cancer. Researchers will collect blood samples from 70 patients before and after standard radiotherapy to see if they can measure tumor changes without surgery. The goal is to create a non-invasive way to monitor how the tumor responds to treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple blood test to monitor brain tumors, reducing the need for invasive biopsies.
What could go wrong
This is an early feasibility study with only 70 participants, so the test may not be sensitive enough or may not work for all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Health Network
Toronto, Ontario, L4W4C2, Canada