New painkiller combo could cut opioid use after keyhole surgery

NCT ID NCT07458282

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a long-acting numbing drug called liposomal bupivacaine, combined with standard bupivacaine, can provide better pain relief after laparoscopic surgery. About 318 adults having gallbladder, hernia, or appendix surgery will receive either the new combo or standard care via a nerve block. The goal is to see if it reduces the need for rescue pain medication and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
liposomal bupivacaine plus bupivacaine
What this could lead to
If it works, this could provide longer-lasting pain relief after laparoscopic surgery, reducing the need for opioids and improving recovery.
What could go wrong
This is a mid-sized trial testing a new combination, so results may not apply to all surgeries. The drug is already approved for other uses, but its safety and effectiveness for this specific procedure are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Tiantan Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100070, China

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