Blood test strategy aims to cut TB treatment dropouts
NCT ID NCT06590428
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether regularly measuring linezolid levels in the blood can prevent dangerous side effects and keep people on their tuberculosis treatment. About 280 adults with rifampin-resistant TB will be randomly assigned to either standard care or dose adjustments based on drug levels. The goal is to reduce treatment interruptions and improve outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
linezolid
What this could lead to
If successful, this approach could help more people complete their TB treatment without dangerous side effects, improving cure rates.
What could go wrong
This is a pragmatic trial, not a new drug. The monitoring strategy may not significantly reduce side effects or may be too complex for routine use.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Nkqubela TB Specialist Hospital
RECRUITINGEast London, Eastern Cape, 5206, South Africa
Contact
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