New hope for Drug-Resistant TB: a 6-Month pill regimen
NCT ID NCT06649721
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 3 trial is testing a 6-month, all-oral combination of four drugs (bedaquiline, delamanid, linezolid, and levofloxacin or clofazimine) to treat rifampin-resistant tuberculosis in Chinese teenagers and adults aged 12 and older. The goal is to see if this shorter regimen is effective and safe. 120 participants will take the pills and be followed for up to 72 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
a combination of bedaquiline, delamanid, linezolid, and levofloxacin or clofazimine
What this could lead to
If successful, this could offer a shorter, all-oral treatment option for drug-resistant tuberculosis, reducing treatment time and side effects.
What could go wrong
This is a single-arm trial with no comparison group, so results may be less reliable. Side effects from the drugs can be serious, and the regimen may not work for everyone.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PULMONARY TUBERCULOSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Anhui Chest Hospital
Hefei, Anhui, China
-
Beijing Chest Hospital
Beijing, China
-
Changsha Central Hospital
Changsha, Hunan, China
-
Harbin Chest Hospital
Harbin, Helongjiang, China
-
Hebei Chest Hospital
Shijiazhuang, Hebei, China
-
Henan Chest Hospital
Zhengzhou, Henan, China
-
Henan Infectious Disease Hospital
Zhengzhou, Henan, China
-
Huashan Hospital
Shanghai, China
-
Hulunbuir Infectious Disease Hospital
Hulunbuir, Inner Mongolia, China
-
Infectious Disease Hospital of Changchun
Changchun, Jilin, China
-
Infectious Disease Hospital of Heilongjiang Province
Harbin, Heilongjiang, China
-
Jiamusi Tuberculosis Hospital(Jiamusi Cancer Hospital)
Jiamusi, Heilongjiang, China
-
Jiangxi Chest Hospital
Nanchang, Jiangxi, China
-
Jilin Tuberculosis Hospital
Jilin City, Jilin, China
-
Linyi People Hospital
Linyi, Shandong, China
-
Liupanshui Third People's Hospital
Liupanshui, Guizhou, China
-
Luoyang Center Hospital
Luoyang, Henan, China
-
Public Health Clinical Center of Chengdu
Chengdu, Sichuan, China
-
Qingdao Chest Hospital
Qingdao, Shandong, China
-
Shandong Public Health Clinical Center, Shandong University
Jinan, Shandong, China
-
Shanxi Medical University Affiliated Chest Hospital
Taiyuan, Shanxi, China
-
Shenyang Chest Hospital
Shenyang, Liaoning, China
-
The 8th Medical Center of Chinese PLA General Hospital
Beijing, Beijing Municipality, China
-
The Fifth Hospital of Shijiazhuang
Shijiazhuang, Hebei, China
-
The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, China
-
The First Affiliated Hospital of Xinxiang Medical University
Xinxiang, Henan, China
-
The Fourth People's Hospital of Nanning
Nanning, Guangxi, China
-
The Second Hospital of Nanjing
Nanjing, Jiangsu, China
-
Tianjin Haihe Hospital
Tianjin, Tianjin Municipality, China
-
Weifang No.2 People's Hospital
Weifang, Shandong, China
-
Wenzhou Central Hospital
Wenzhou, Zhejiang, China
-
Wuhan Pulmonary Hospital，Wuhan Tuberculosis Prevention and Control Institute
Wuhan, Hubei, China
-
Xi'an Chest Hospital
Xi'an, Shaanxi, China
-
Yantai Qishan Hospital
Yantai, Shandong, China