Light therapy for depression: scientists hunt for clues to predict who will respond
NCT ID NCT07462637
First seen Apr 01, 2026 · Last updated Jun 23, 2026 · Updated 14 times
Summary
This study aims to find biological markers that predict how well people with major depressive episodes respond to light therapy. Researchers will treat 173 adults with unipolar or bipolar depression using a bright light box for 4 weeks. By measuring sleep, mood, and circadian rhythms before and after treatment, they hope to identify a 'signature' of response, potentially personalizing light therapy for different depression subtypes.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE EPISODE are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Bichat - Claude-Bernard Hospital
Paris, 75018, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Light therapy (10,000-lux fluorescent white light box)
What this could lead to
If successful, this could help doctors predict which patients with depression will benefit most from light therapy, leading to more personalized and effective treatment.
What could go wrong
This is an early-stage observational study, not a treatment trial. It may not identify clear biomarkers, and results may not apply to all depression types.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.