Lifestyle makeover may shield aging brains

NCT ID NCT05256199

Ongoing Prevention Sponsor: Alzheimercentrum Amsterdam Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a personalized lifestyle program can prevent or slow cognitive decline in older adults (ages 60-79) who have risk factors like high blood pressure or lack of exercise. Over 1,200 participants will either receive intensive coaching on diet, exercise, and brain training, or just general health information online. The goal is to see if the active program improves memory and thinking skills after two years.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Risk Reduction Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE DECLINE LIFE STYLE RISK REDUCTION

Contacts and locations

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Locations

Alzheimer Center Amsterdam

Amsterdam, 1671 EA, Netherlands
Maastricht University

Maastricht, Netherlands
Radboud University

Nijmegen, Netherlands
University Medical Center Groningen

Groningen, Netherlands
Wageningen Unversity and Research

Wageningen, Netherlands