Can a simple IV drip stop pain that lasts a year after surgery?

NCT ID NCT05072314

Summary

This large international study is testing if giving patients a lidocaine (a common numbing medicine) infusion during and for 24 hours after breast cancer surgery can prevent them from developing moderate or severe chronic pain one year later. It will enroll 4,300 women and compare the lidocaine infusion to a placebo (saltwater) drip. The main goal is to see if this approach safely reduces the chance of long-term pain, while also measuring pain levels, opioid use, and quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anaesthetic Group Ballarat

    TERMINATED

    Ballarat, Victoria, 3350, Australia

  • Auckland City Hospital

    RECRUITING

    Auckland, Auckland, 1023, New Zealand

  • Ballarat Health Services (Grampians Health)

    RECRUITING

    Ballarat, Victoria, 3350, Australia

  • Barwon Health - University Hospital Geelong

    RECRUITING

    Geelong, Victoria, 3220, Australia

  • Belfast City Hospital

    RECRUITING

    Belfast, BT9 7AB, United Kingdom

  • Blacktown Mount Druitt Hospital

    RECRUITING

    Mount Druitt, New South Wales, 2770, Australia

  • Darlington Memorial Hospital

    COMPLETED

    Darlington, DL3 6HX, United Kingdom

  • Flinders Medical Centre

    RECRUITING

    Bedford Park, South Australia, 5042, Australia

  • Gold Coast Hospital and Health Service- Gold Coast University Hospital

    TERMINATED

    Southport, Queensland, 4215, Australia

  • Goulburn Valley Health

    TERMINATED

    Shepparton, Victoria, 3630, Australia

  • Latrobe Regional Hospital

    WITHDRAWN

    Traralgon, Victoria, 3844, Australia

  • Mackay Base Hospital

    RECRUITING

    Mackay, Queensland, 4740, Australia

  • Maroondah Hospital - Eastern Health

    RECRUITING

    Ringwood East, Victoria, 3135, Australia

  • Middlemore Hospital

    RECRUITING

    Auckland, Middlemore, 2025, New Zealand

  • Monash Health - Moorabbin Hospital

    COMPLETED

    Melbourne, Victoria, 3165, Australia

  • Nepean Hospital

    RECRUITING

    Kingswood, New South Wales, 2747, Australia

  • Newcastle upon Tyne Hospitals

    RECRUITING

    Newcastle upon Tyne, United Kingdom

  • Norfolk and Norwich University Hospital

    RECRUITING

    Norwich, NR4 7UY, United Kingdom

  • North District Hospital

    RECRUITING

    Shatin, Sha Tin, Hong Kong

  • Northern Hospital

    WITHDRAWN

    Melbourne, Victoria, 3076, Australia

  • Pamela Youde Nethersole Eastern Hospital

    RECRUITING

    Chai Wan, Hong Kong

  • Princess Alexandra Hospital

    RECRUITING

    Woolloongabba, Queensland, 4102, Australia

  • Queen Elizabeth II Jubilee Hospital

    RECRUITING

    Coopers Plains, Queensland, 4108, Australia

  • Rockhampton Hospital

    TERMINATED

    Rockhampton, Queensland, 4700, Australia

  • Rotherham NHS Foundation Trust

    RECRUITING

    Rotherham, S60 2UD, United Kingdom

  • Royal Brisbane and Women's Hospital

    RECRUITING

    Brisbane, Queensland, 4029, Australia

  • Royal Hallamshire Hospital

    RECRUITING

    Sheffield, S10 2JF, United Kingdom

  • Royal Hobart Hospital

    RECRUITING

    Hobart, Tasmania, 7000, Australia

  • Royal Liverpool and Broadgreen Hospitals

    RECRUITING

    Liverpool, United Kingdom

  • Royal Marsden Hospital - London and Sutton

    RECRUITING

    London, United Kingdom

  • Royal Melbourne Hospital

    RECRUITING

    Melbourne, Victoria, 3050, Australia

  • Royal North Shore Hospital

    RECRUITING

    Sydney, New South Wales, 2035, Australia

  • Royal Perth Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

  • Russells Hall Hospital

    RECRUITING

    Dudley, DY1 2HQ, United Kingdom

  • Ruttonjee Hospital

    RECRUITING

    Wan Chai, Hong Kong

  • Southmead Hospital, North Bristol Trust

    RECRUITING

    Bristol, BS10 5NB, United Kingdom

  • St George Hospital

    RECRUITING

    Sydney, New South Wales, 2217, Australia

  • St Helen's Hospital

    RECRUITING

    St Helens, WA9 3DA, United Kingdom

  • St John of God Subiaco

    RECRUITING

    Perth, Western Australia, 6008, Australia

  • St Vincent's Hospital Melbourne

    RECRUITING

    Melbourne, Victoria, 3065, Australia

  • The Alfred

    RECRUITING

    Melbourne, Victoria, 3004, Australia

  • Torbay Hospital

    ACTIVE_NOT_RECRUITING

    Torquay, TQ2 7AA, United Kingdom

  • University Hospital Southampton

    RECRUITING

    Southampton, United Kingdom

  • University Hospital Wishaw

    RECRUITING

    Wishaw, Scotland, United Kingdom

  • Waikato Hospital

    RECRUITING

    Hamilton, Waikato Region, 3204, New Zealand

  • Westmead Hospital

    RECRUITING

    Sydney, New South Wales, 2145, Australia

  • Whittington Hospital

    RECRUITING

    London, N19 5NF, United Kingdom

Conditions

Explore the condition pages connected to this study.