New heart failure drug trial aims to ease breathing and save lives

NCT ID NCT07262723

Not yet recruiting Disease control Sponsor: Chittagong Medical College Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether levosimendan, a drug that strengthens heart contractions without increasing oxygen demand, can help people hospitalized with acute decompensated heart failure. About 332 adults will receive either levosimendan plus standard care or standard care alone. Researchers will track symptom improvement, side effects, and survival over 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Levosimendan
What this could lead to: If it works, this could provide a new treatment option for acute heart failure, improving symptoms and reducing hospital stays.
What could go wrong: This is a Phase 2/3 trial, so results are not yet proven. The drug may not show significant benefit over standard care, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congestive heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE DECOMPENSATED HEART FAILURE (ADHF)

Contacts and locations

Locations

Apollo Imperial Hospital & Max Hospital

Chittagong, 4202, Bangladesh
Chattogram Maa-O-Shishu Hospital Medical College Hospital

Chittagong, 4100, Bangladesh
Chittagong Medical College Hospital, Chattogram

Chittagong, 4000, Bangladesh
Cox's Bazar Medical College

Cox’s Bāzār, 4700, Bangladesh
National Institute of Cardiovascular Diseases

Dhaka, 1207, Bangladesh
United Hospital Limited

Dhaka, 1212, Bangladesh

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