New heart failure drug trial aims to ease breathing and save lives

NCT ID NCT07262723

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether levosimendan, a drug that strengthens heart contractions without increasing oxygen demand, can help people hospitalized with acute decompensated heart failure. About 332 adults will receive either levosimendan plus standard care or standard care alone. Researchers will track symptom improvement, side effects, and survival over 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Levosimendan

What this could lead to

If it works, this could provide a new treatment option for acute heart failure, improving symptoms and reducing hospital stays.

What could go wrong

This is a Phase 2/3 trial, so results are not yet proven. The drug may not show significant benefit over standard care, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congestive heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Apollo Imperial Hospital & Max Hospital

    Chittagong, 4202, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chattogram Maa-O-Shishu Hospital Medical College Hospital

    Chittagong, 4100, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chittagong Medical College Hospital, Chattogram

    Chittagong, 4000, Bangladesh

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cox's Bazar Medical College

    Cox’s Bāzār, 4700, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • National Institute of Cardiovascular Diseases

    Dhaka, 1207, Bangladesh

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • United Hospital Limited

    Dhaka, 1212, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact