Kidney function may change how antibiotic levornidazole acts in the body

NCT ID NCT07033182

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study looks at how a single dose of the antibiotic levornidazole is processed by the body in people with moderate or severe kidney impairment compared to healthy volunteers. Researchers will measure drug levels in the blood and urine, and monitor safety. The goal is to understand whether kidney function affects how the drug is cleared, which could guide future dosing recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

levornidazole disodium phosphate

What this could lead to

If successful, this could help doctors determine safe dosing of levornidazole for patients with kidney impairment.

What could go wrong

This is a small, early-phase study focused on drug processing, not on treating infections. Results may not apply to real-world use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anaerobic bacteria infectious disease chronic kidney disease impaired renal function disease kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, China