Fertility drug combo may boost baby chances for women with irregular periods

NCT ID NCT06934785

Recruiting now Disease control Sponsor: Mỹ Đức Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study tests whether taking two fertility drugs together (letrozole and clomiphene citrate) works better than letrozole alone for women with ovulation disorders who are trying to conceive. Researchers will compare live birth rates after one treatment cycle in 600 women across six clinics in Vietnam. The goal is to see if the combination leads to more successful pregnancies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: letrozole and clomiphene citrate
What this could lead to: If successful, this combination could offer a more effective fertility treatment for women with ovulation problems, increasing their chances of having a baby.
What could go wrong: This is a mid-stage trial, and the expected improvement is modest (10% increase in live births). Results may not apply to all populations, and side effects from the drugs are possible.

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Conditions

The condition(s) this trial relates to.

anovulation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLOMIPHENE CITRATE LETROZOLE OVULATION DISORDER OVULATION INDUCTION

Contacts and locations

Locations

My Duc Hospital
RECRUITING

Ho Chi Minh City, Ho Chi Minh City, 70000, Vietnam

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