New drug cocktail shows promise for Hard-to-Treat blood cancers

NCT ID NCT02160015

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 26 times

Summary

This early-phase trial is testing a combination of three drugs—lenalidomide, ibrutinib, and rituximab—in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has returned or not responded to prior treatments. The main goal is to find the safest dose and check for side effects. The study involves 12 participants and is no longer recruiting new patients.

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Contacts and locations

Locations

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

Conditions

Explore the condition pages connected to this study.