Stem cell transplant study seeks best way to prevent immune attack

NCT ID NCT01231412

First seen May 06, 2026 · Last updated Jun 13, 2026 · Updated 9 times

Summary

This study tested different drug combinations to prevent graft-versus-host disease (GVHD) in 174 people with blood cancers receiving stem cells from an unrelated donor. GVHD is a serious side effect where donor cells attack the patient's body. The goal was to find which drug regimen works best to control this risk while still allowing the transplant to succeed.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, 8200, Denmark

  • Emory University/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

  • Medizinische Univ Klinik Koln

    Cologne, 50924, Germany

  • Presbyterian - Saint Lukes Medical Center - Health One

    Denver, Colorado, 80218, United States

  • Rigshospitalet University Hospital

    Copenhagen, 2100, Denmark

  • Universitaet Leipzig

    Leipzig, D-04103, Germany

  • University of Colorado

    Denver, Colorado, 80217-3364, United States

  • University of Tuebingen-Germany

    Tübingen, D-72076, Germany

  • VA Puget Sound Health Care System

    Seattle, Washington, 98101, United States

Conditions

Explore the condition pages connected to this study.