New drug combo shows early promise for recurrent lymphoma

NCT ID NCT01644799

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested two drugs, lenalidomide and idelalisib, in 8 people with follicular lymphoma that had returned after previous treatment. Lenalidomide helps the immune system fight cancer, while idelalisib blocks enzymes that cancer cells need to grow. The main goal was to find the safest dose and check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lenalidomide and idelalisib

What this could lead to

If this combination proves safe and effective, it could offer a new treatment option for people with recurrent follicular lymphoma.

What could go wrong

This is a very early, small phase I trial with only 8 participants, so results may not apply broadly. The main goal is safety, not yet effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Ohio State University Medical Center

    Columbus, Ohio, 43210, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Weill Medical College of Cornell University

    New York, New York, 10065, United States