Lifestyle makeover may boost breast cancer treatment success

NCT ID NCT07066189

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 39 times

Summary

This study tests whether a structured nutrition and exercise program can improve the chance of a complete response to pre-surgery chemo-immunotherapy in women with triple-negative breast cancer. About 160 women who are not currently exercising or eating many fruits and vegetables will be randomly assigned to either the lifestyle program or usual care. The goal is to see if those in the program have no cancer remaining in the breast or lymph nodes at the time of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06511, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exercise and medical nutrition program

What this could lead to

If it works, this could show that a structured lifestyle program helps more women achieve a complete response to pre-surgery treatment for triple-negative breast cancer.

What could go wrong

This is a relatively small, early-stage behavioral trial, so results may not be conclusive or widely applicable. The intervention is added on top of standard treatment, so its independent effect may be hard to measure.

Conditions

The condition(s) this trial relates to.

Motor Activity Pathologic Complete Response triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.