Laser precision could halt keratoconus progression and sharpen vision

NCT ID NCT03760432

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a laser-guided procedure to treat keratoconus, a condition where the cornea thins and bulges, causing blurry vision. The procedure uses OCT scans to plan a custom laser treatment that smooths the cornea and strengthens it with cross-linking. Researchers aim to see if this improves vision more than standard care. The trial is recruiting 100 participants with keratoconus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Laser Custom Corneal Collagen Cross-Linking (a procedure using a laser and cross-linking to reshape and strengthen the cornea)

What this could lead to

If successful, this could offer a more precise, vision-improving treatment for keratoconus that strengthens the cornea and reduces the need for glasses or contact lenses.

What could go wrong

This is an early-stage study with no phase designation, so the procedure may not prove effective or safe for everyone. Risks include infection, scarring, or no improvement in vision.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

keratoconus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••