Lactate: a surprising booster for failing hearts?

NCT ID NCT06121323

Completed Knowledge-focused Sponsor: Henrik Wiggers Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how lactate, a natural substance made by the body, affects heart function in 12 people with chronic heart failure. Researchers gave lactate as an infusion and as a drink, then measured changes in blood flow and heart pressure. The goal was to understand if lactate could help the heart work better, but this was a small, early study to gather information, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sodium lactate
What this could lead to: If it works, this could point toward new ways to manage heart failure by using lactate to improve heart function.
What could go wrong: This is a very small, early-stage study with only 12 participants, so results may not apply to everyone. It is designed to understand basic effects, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE, SYSTOLIC

Contacts and locations

Locations

Aarhus University Hospital

Aarhus, Central Jutland, 8200, Denmark

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