Could a seizure drug ease pain for chronic pancreatitis patients on opioids?
NCT ID NCT05603702
First seen Mar 18, 2026 · Last updated Jun 13, 2026 · Updated 14 times
Summary
This early-phase study tests whether adding lacosamide, a seizure medication, to opioid therapy is safe and tolerable for people with chronic pancreatitis and ongoing abdominal pain. The goal is to reduce a condition called opioid-induced hyperalgesia, where opioids actually make pain worse. About 21 adults who are already on stable opioid treatment will take lacosamide for 7 days and be monitored for side effects and pain changes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Indiana University
Indianapolis, Indiana, 46202, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Ohio State University
Columbus, Ohio, 43210, United States
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Stanford University
Stanford, California, 94305, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Conditions
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