Kratom put to the test: first safety study in opioid users

NCT ID NCT06072170

Completed Knowledge-focused Sponsor: Altasciences Company Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested single doses of kratom in 40 healthy adults who have used opioids recreationally. Researchers measured safety, side effects, and how the body processes kratom. The goal was to gather basic information, not to treat any condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: kratom
What this could lead to: If successful, this study could provide basic safety data to guide future research on kratom's potential uses.
What could go wrong: This is an early Phase 1 study with only 40 participants, so results may not apply to the general population. Kratom's safety and effects are still poorly understood.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PHARMACODYNAMICS PHARMACOKINETICS SAFETY

Contacts and locations

Locations

Altasciences Clinical Kansas, Inc.

Overland Park, Kansas, 66212, United States

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