Kratom put to the test: first safety study in opioid users

NCT ID NCT06072170

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested single doses of kratom in 40 healthy adults who have used opioids recreationally. Researchers measured safety, side effects, and how the body processes kratom. The goal was to gather basic information, not to treat any condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

kratom

What this could lead to

If successful, this study could provide basic safety data to guide future research on kratom's potential uses.

What could go wrong

This is an early Phase 1 study with only 40 participants, so results may not apply to the general population. Kratom's safety and effects are still poorly understood.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Altasciences Clinical Kansas, Inc.

    Overland Park, Kansas, 66212, United States