Oxygen-Boosting injection may help rectal cancer patients avoid surgery

NCT ID NCT07622017

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a special solution (KRC-01) into rectal tumors before radiation can make the radiation work better. The solution increases oxygen inside the tumor, which helps radiation kill cancer cells. About 24 adults with advanced rectal cancer that hasn't spread will receive this treatment along with standard chemoradiotherapy. The goal is to see if more patients can achieve a complete response and possibly avoid surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gustave Roussy

    Villejuif, Val de Marne, 94800, France

  • Institut Bergonié

    Bordeaux, 33000, France

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