Oxygen-Boosting injection may help rectal cancer patients avoid surgery

NCT ID NCT07622017

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a special solution (KRC-01) into rectal tumors before radiation can make the radiation work better. The solution increases oxygen inside the tumor, which helps radiation kill cancer cells. About 24 adults with advanced rectal cancer that hasn't spread will receive this treatment along with standard chemoradiotherapy. The goal is to see if more patients can achieve a complete response and possibly avoid surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gustave Roussy

    Villejuif, Val de Marne, 94800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Bergonié

    Bordeaux, 33000, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••