Knee surgery pain relief: which nerve block works best?
NCT ID NCT07092982
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of nerve blocks for pain after total knee replacement. One method uses a combination of adductor canal and iPACK blocks, the other uses a suprainguinal fascia iliaca block. The goal is to see which provides better pain control, reduces opioid use, and lowers stress on the body. Fifty-two adults having knee replacement will be randomly assigned to one of the two groups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bupivacaine (a numbing medicine)
What this could lead to
If one nerve block method proves better, it could lead to less pain and opioid use after knee replacement surgery.
What could go wrong
This is a small, early-phase study with only 52 patients. Results may not apply to everyone, and both methods are already in use, so no major breakthrough is expected.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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SB Istanbul Education and Research Hospital
RECRUITINGIstanbul, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••