Microspheres aim to ease knee pain without surgery
NCT ID NCT06872567
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new procedure called genicular artery embolization (GAE) using Nexsphere-F microspheres against standard steroid injections for knee osteoarthritis. About 126 people with knee pain will be randomly assigned to one of the two treatments. The goal is to see if the microspheres can better reduce pain, stiffness, and daily activity limitations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nexsphere-F microspheres (resorbable embolization beads)
What this could lead to
If it works, this could offer a new, longer-lasting option for knee osteoarthritis pain relief without surgery.
What could go wrong
This is an early-stage trial with only 126 people, so results may not apply to everyone. Risks include allergic reactions or complications from the artery procedure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States