Could donor tissue replace metal knee implants?

NCT ID NCT07769632

NEW Not yet recruiting ⭐️ CURE ⭐️ Sponsor: AlSalam Hospital Source: ClinicalTrials.gov ↗

First seen Aug 18, 2026 · Last updated Aug 18, 2026

Summary

This trial is testing a new type of knee replacement for younger patients with severe knee osteoarthritis. Instead of the standard metal and plastic implant, surgeons will use a graft made of donor bone, cartilage, and meniscus to replace the damaged parts of the knee. The goal is to see if this biological approach can provide better range of motion, allowing patients to sit on the floor and maintain an active lifestyle. The study will measure how well the graft fuses with the patient's own bone and assess pain, stiffness, and physical function using the WOMAC score.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
allogenic bone and cartilage graft
What this could lead to
If successful, this could offer a more natural knee replacement option that preserves greater range of motion, potentially allowing patients to sit on the floor and maintain an active lifestyle.
What could go wrong
This is a very early, small trial (10 participants). The graft may fail to fuse with the native bone, and there are risks of infection, rejection, or the procedure not providing lasting benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS (OA) OF THE KNEE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AlSalam Specialist Hospital

    Manama, 80278, Bahrain

More trials for these conditions

Other studies related to the condition(s) this trial covers.