Scientists use MRI to uncover muscle secrets behind knee pain
NCT ID NCT01862731
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the thigh muscles control the movement of the knee cap in people with long-term knee cap pain. Researchers will use MRI scans to compare knee movement in people with pain and healthy volunteers. In a second session, they will temporarily numb a thigh muscle with an injection to see how that changes knee cap movement and pain. The goal is to better understand the muscle's role in knee pain, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
local anesthetic injection into the thigh muscle
What this could lead to
If successful, this could help explain why some people develop chronic knee cap pain, potentially guiding future treatments.
What could go wrong
This is a small, early-stage observational study with only 35 participants. It is not testing a treatment, so it may not lead directly to any new therapy.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PATELLOFEMORAL PAIN SYNDROME are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States